In the post, we will compare the Pfizer vs. Moderna COVID-19 vaccines, see their pros and cons, and discuss their similarities and differences. Pfizer Moderna Vaccine Shipments The minimum vaccine order for direct shipment from Pfizer is 975 doses. Keith began writing for the Fool in 2012 and focuses primarily on healthcare investing topics. Both vaccines appeared to be equally effective across different age and ethnic groups and races. The fragment stimulates antibody production, which eventually provides an immune response against the virus. The biotech has also secured a supply deal with Canada and is in discussions about an agreement with the European Commission. It’s undoubtedly going to take some time to figure out the durability of both the vaccines’ protection. Here's how Moderna and Pfizer compare. Emergency Use Authorization (EUA) by late November. Here is what you need to know about how the Pfizer and Moderna vaccines compare. Moderna (NASDAQ:MRNA) makes one of the vaccine candidates in the running. Moderna’s vaccine stays stable in the fridge for up to 30-days and up to 12-hours at room temperature after thawing. According to the Centers for Disease Control and Prevention (CDC), once the vaccine is administered, the mRNA will bind to the immune cells, and the human cells use them to make the corresponding protein piece. Of course, Pfizer isn't dependent only on BNT162b2. Stock Advisor launched in February of 2002. Moderna vaccine vs. Pfizer Vaccine: Experts say both are safe and effective A.J. Both companies have recently begun testing their vaccine on participants of 12- to 17-year-olds. However, the COVID-19 vaccines by Pfizer and Moderns work using messenger RNA (mRNA). Author: Marcelino Benito (KHOU) While severe reactions were not reported in clinical trials, it is essential to note that the FDA does not currently advise individuals with life-threatening allergies to receive the vaccination at this time. By: Julia Fello Researchers have blessed us with Covid-19 vaccines in record time—the process could have taken them 10 to 15 years, but the U.S. Food and Drug Administration has granted emergency authorization to vaccines made by Pfizer-BioNTech and Moderna in less than a year. Both Pfizer and Moderna vaccinations have similar side effects. In this fight against the COVID-19 pandemic, Pfizer and Moderna vaccines are the first contenders in the race. Once your body creates the expected immune response, your body eliminates the protein and mRNA while the produced antibodies provide you protection. Image source: Getty Images. The Pfizer emergency use authorization is for anyone of or above 16 years. Studies on the Moderna vaccine also claim that the vaccine may interfere and cause allergic reactions in people with facial fillers. After moving from biotechnology to business operations in just three years, Chitra then made a drastic drift to start her freelance content writing and online marketing career. If this mRNA approach works for one disease, it will likely work for many others. That turned out to be a smart move for Pfizer. Market data powered by FactSet and Web Financial Group. Following the Food and Drug Administration’s emergency use authorization, two vaccines are now available for Americans. While vaccines can help build immunity, there is not a silver bullet to stop the pandemic. There is no “best” vaccine option to stop the spread of the disease. Since then, the company's shares have skyrocketed close to 280%. It offers a solid dividend with decent, albeit not spectacular, growth prospects that should improve in the near future when the Upjohn-Mylan transaction closes. The minimum vaccine order for direct shipment from McKesson is 100 doses. Aggressive investors will likely prefer Moderna. Indeed, it remains unclear how both vaccines will stack up over the long term. This is also one of the most significant differences noted between the Pfizer-BioNTech and Moderna vaccine. If the FDA authorizes Moderna's COVID-19 vaccine, 5.9 doses could be shipped out by next week. The Pfizer vaccine has a slightly higher efficacy rate measured during the last clinical trial stage. The Moderna’s vaccine must be shipped at -4 Fahrenheit, the temperature in a regular refrigerator. Call us today and let us help you. The company is evaluating five other mRNA vaccine candidates in clinical testing. This process will also involve watching reports that the immunized population is starting to contract COVID-19 disease in larger numbers. We should know pretty soon if that's the case. Only two coronavirus vaccines have a realistic possibility of becoming available by the end of 2020. A freezer unit with -94 Fahrenheit is required to ship and store the Pfizer vaccine. While the deal will also reduce Pfizer's dividend a little, the company will still offer one of the more attractive dividends in the healthcare sector. Unlike the flu vaccine, no actual virus is used in this case. Author: Thuy Lan Nguyen This article represents the opinion of the writer, who may disagree with the “official” recommendation position of a Motley Fool premium advisory service. Employee Health Medical Management Experts. Its most significant growth drivers include blood thinner Eliquis, cancer drugs Ibrance and Xtandi, and rare disease drug Vyndaqel. Moderna expects to charge between $25 and $37 per dose of the vaccine for some, and Pfizer and BioNTech are anticipating charging $20 per dose of their vaccine, CNBC reported. If the vaccine wins EUA, Pfizer and BioNTech stand to receive $1.95 billion from the U.S. government to supply 100 million doses. We’re motley! Could Coronavirus Variants Boost Pfizer's Vaccine Sales By 50%? A number of coronavirus vaccines are coming to market and there are some differences to know about. His background includes serving in management and consulting for the healthcare technology, health insurance, medical device, and pharmacy benefits management industries. Pfizer vs. Moderna COVID-19 vaccines - What's the difference? That experimental vaccine, mRNA-1273, has moved quickly through clinical trials. Should You Be Concerned About mRNA COVID Vaccines? The biotech's market cap currently stands at a little under $30 billion. Moderna has already begun rolling regulatory submissions for its coronavirus vaccine in Canada and received a green light to file for European approval. That deal could be expanded to include another 500 million doses. In contrast, Moderna’s authorized COVID-19 vaccine is for people 18 and older. In such a situation, there might be a recommended booster shot at some interval. While the pharmaceutical company Pfizer was the first to reach the finish point of vaccine development, the biotechnology company Moderna was the second company to get the EUA from the United States FDA. While storage and distribution may not be an issue for hospitals and healthcare organizations, small distribution chains and public health clinics may find this to be an ongoing concern with regards to vaccine storage and distribution. Unlike traditional attenuated microbial injections, these mRNA vaccines work by encoding a fragment or portion of the SARS-CoV-2 virus’ spike protein into human cells. Both vaccines were measured based on providing immune response and shipping symptomatic COVID infection. Most human vaccines are attenuated virus or bacterial based immune-boosting options. However, it is still unknown how long each vaccine will provide immunity against the virus. It could submit for U.S. 3 Reasons to Buy Pfizer and 1 Reason to Sell, 3 Popular Stocks Billionaires Can't Stop Selling, Copyright, Trademark and Patent Information. During its last stage of clinical trial, the Moderna vaccine was 94.1% effective at preventing symptomatic Covid-19. Since both the vaccines are new, there might be a possibility of offering at least one booster dose after the initial vaccination’s first two dosages. The US Food and Drug Administration has approved for emergency use 2 vaccines against the coronavirus disease 2019 (COVID-19), one from Pfizer-BioNTech (December 11, 2020) and the other from Moderna (December 18, 2020). Better Buy: Moderna vs. BioNTech ... After yesterday's news demonstrating the efficacy of the Pfizer/BioNTech vaccine candidate, investors may think the battle here is over. Questioning an investing thesis -- even one of our own -- helps us all think critically about investing and make decisions that help us become smarter, happier, and richer. If not complete elimination, both vaccines seemed to reduce the risk of severe COVID-19 disease. The encoded proteins, then,  spark an immune response that promotes immune response against the COVID-19 virus. However, they'll appeal to different kinds of investors. Founded in 1993 by brothers Tom and David Gardner, The Motley Fool helps millions of people attain financial freedom through our website, podcasts, books, newspaper column, radio show, and premium investing services. In addition to the vaccinations, we should wear masks, follow hand hygiene, and social distancing to help our community fight the disease. Returns as of 03/05/2021. With Axiom, as a content marketing specialist, she is passionate about creating informative marketing copies. Even though both vaccines use a similar mRNA platform, only Pfizer has a more stringent storage requirement. The biotech's shares will almost certainly move a lot higher than Pfizer stock will if both companies win EUA for their respective coronavirus vaccines. However, the company has bought several ultra-cold storage freezers to ease the vaccine distribution burden. Most of the gain has come this year after Moderna announced it was developing a coronavirus vaccine candidate. Race to Emergency Use Authorization (EUA): Pfizer vs. Moderna COVID-19 Vaccines – Similarities: Pfizer vs. Moderna COVID-19 vaccines – Differences: Johnson & Johnson Single-Dose Vaccine – Things You Need To Know, Occupational Health Management and Programs, Return to Work Occupational Health Programs, Swelling at the injection site and redness. While both vaccines have nearly similar immune responses, the Pfizer vaccine showed the efficacy of 95%, and the Moderna showed the efficacy of 94%. Pfizer (NYSE:PFE), along with its partner BioNTech (NASDAQ:BNTX), lays claim to the other contender. The case for Moderna. Assuming all goes well, Moderna will have an instant blockbuster product on its hands. On the other hand, Pfizer's the better pick for more conservative investors. While Moderna and Pfizer share this one important thing in common, the two drugmakers are quite different in many respects. Pfizer vaccine has an ultra-cold storage requirement, which technically makes it challenging to store and distribute appropriately. Pfizer recognized the potential for mRNA vaccines in 2018 when it partnered with BioNTech to develop an mRNA flu vaccine. Moderna is banking on mRNA in a big way. The big pharma stock is less risky than Moderna. Moderna’s clinical trial had 30,350 participants, Pfizer’s 36,621. Its pipeline also includes seven mRNA programs targeting conditions such as cancer and coronary artery disease. The big drugmaker expanded its relationship with the German biotech earlier this year to advance its coronavirus vaccine program. Which of these coronavirus-focused stocks is the better pick for investors over the long term? Pfizer vs. Moderna: Is one better than the other? Moderna's initial public offering (IPO) in December 2018 was the biggest ever for a biotech stock. While both vaccines use a similar mRNA platform and immune response mechanism, both vaccines have different immune response levels. Investors, in turn, are banking on Moderna's success. Vaccine developers have plans to perform periodic tests by drawing blood from some volunteers to see their antibody levels. The two companies hope to file for EUA with the U.S. Food and Drug Administration for experimental coronavirus vaccine BNT162b2 by the third week of November. These supply agreements are contingent upon mRNA-1273 proving to be safe and effective. My view is that both Moderna and Pfizer are attractive stocks. Moderna's initial public offering (IPO) in December 2018 was the biggest ever for a biotech stock. Both vaccines are now tested against the newly discovered, highly contagious COVID-19 strains. In contrast to Pfizer, Moderna’s vaccine doesn’t require ultra-cold temperature for storage and distribution. Cumulative Growth of a $10,000 Investment in Stock Advisor, Better Coronavirus Stock: Moderna vs. Pfizer @themotleyfool #stocks $PFE $MRNA $MYL $BNTX, file for EUA with the U.S. Food and Drug Administration. If mRNA-1273 wins regulatory clearance, the stock could move much higher. Along the way, Moderna has racked up nearly $2.5 billion in funding from the U.S. government, including a deal to supply 100 million doses of its vaccine. However, experts have confirmed that a decline in antibody levels doesn’t necessarily equate to reducing the immune response against the virus. It has 90 clinical programs, with four of those awaiting regulatory approval and another 23 in late-stage testing.
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