Since 1982, when the Korea Bee Sting Institute was founded, 8,730 persons have experienced bee sting therapy. In a study using the mouse air pouch model, dilute bee venom (dBV) treatment produced a potent anti-inflammatory effect, as indicated by a marked reduction in leukocyte migration compared with that of saline pre-treatment. According to the Russian Institute, … Though promising, more high-quality studies are needed to confirm these effects (14). The bee venom is used for the treatment of rheumatic diseases, multiple sclerosis, rheumatic fever, high blood pressure, sciatica, psoriasis, hematomas, various skin conditions, and burns, among other. Additionally, venom immunotherapy, in which bee venom is administered by a healthcare professional by injection — is used to treat people with severe allergies to bee stings. The medicinal use of bee venom dates back to ancient Egypt and is reported in the history of... Current Medicinal Claims. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Although bee venom has recently experienced a surge in popularity, bee-venom therapy has been used in traditional medicine practices for thousands of years (6). Bee venom or other honeybee products are ineffective for the treatment or prevention of cancer. However, bee venom has many positive properties, therefore, in traditional and alternative medicine is used more often. Other animal studies suggest that bee-venom therapy may also help treat allergic conditions like asthma (21, 22). In one of the alternative medical uses of honey bee products, apitherapy, bee venom has been used to treat arthritis and other painful conditions. 2017. Bee-venom therapy should only be administered by medical professionals. This extracted venom is said to reduce wrinkles and plump lips when applied to the skin. After the bee venom lotion was applied I was left alone for 20 minutes to allow the cream to penetrate deep into my skin. We comply with the HONcode standard for trustworthy health information -. When bees are swallowed, life-threatening pharyngeal edema and respiratory obstruction may occur. Venom is the special superpower granted by the Bee Miraculous to its owner. Our Bee Venom range is high-performance, next generation skin care. This information is not specific medical advice and does not replace information you receive from your health care provider. Can You Eat Honeycomb? Honeybee venom treatment of rats with adjuvant arthritis inhibits certain macrophage activities and, thus, indirectly inhibits the activation of T and B cells.Hadjipetrou-Kourounakis 1988, Treatment with bee venom resulted in a reduction of tissue swelling and osteophyte formation in a model of chronic arthritis, as well as reduction of edema formation in a model of acute arthritis.Reisman 1992, Bee venom inhibited lipopolysaccharide-induced prostaglandin E 2 and nitric oxide production in Raw 264.7 cells. Benefits, Uses, and Dangers, Bee Sting Allergy: Symptoms of Anaphylaxis. Importantly, while research shows that some compounds in the venom may have beneficial properties, the isolated effects of each component are unknown, as many components have not been well studied (5). This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. bee venom uses | Bee venom is given as a shot of bee stings and some of bee venom uses is for rheumatoid arthritis, nerve pain , Ms, reducing allergy (desensitization) to them (venom immunotherapy), swollen tendons and so on. Bee venom is a natural product that has risen in popularity due to its variety of potential health benefits. However, using bee-venom products or undergoing bee-venom therapy may cause serious side effects, so be sure to practice caution and consult a trained medical professional for advice before trying it out. Bee strings are never fun, but for most people they’re just a temporary jolt of pain, swelling, and redness. An elevated superoxide level has been suggested as a possible cause of oxidative damage to synovial fluid and other joint membranes. Bee venom is used to hyposensitize individuals highly sensitive to bee stings. Systemic pretreatment with the beta-adrenergic receptor antagonist propranolol, but not the corticosteroid antagonist RU-486, inhibited dBVAI. Bees inject the poison with their stings, although male bees do not possess these. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. Criteria to precisely identify the point in time when protection becomes persistent are unknown. Medically reviewed by Drugs.com. Here’s our process. Featuring a unique blend of Bee Venom, Stem Cells and award-winning peptide technology. Melittin and other agents that bind calmodulin have decreased superoxide production. Although these potential benefits are promising, more research is needed to confirm them. Bee venom and its various uses.Bee venom and its various uses.Bee venom and its various uses.Bee venom and its various uses. For this reason, you should exercise extreme caution when using these products or treatments. Report aired December 12. It refers to any use of venom to assist the body in healing itself. These findings suggest that several mechanisms play an interrelated role in the development of immunity to honeybee venom. Bee venom has been used for thousands of years to treat pain and inflammation. Some substances in bee venom, including melittin and apamin, may have medicinal properties. We’ll explain its benefits and side effects to watch for. As the name implies, bee venom is an ingredient derived from bees. Intrathecal administration of a muscarinic type 2 (M2) receptor antagonist (methoctramine), but not M1or M3 receptor antagonists, abolished dBVAI, indicating that spinal M2 receptors are specifically involved in dBVAI.Yoon 2005. You should talk with your health care provider for complete information about the risks and benefits of using this product. How to use a bee venom cream. Bee venom is used to hyposensitize individuals highly sensitive to bee stings. They are collected from the insects and diluted to standardized concentrations. While not all of the purported benefits of bee venom are backed by science, research has shown that it has several powerful medicinal properties. It’s used as a natural treatment for a variety of ailments. It’s recommended to try a small amount first and leave it for 24 hours to ensure no irritation or adverse reaction occurs from its use. You can purchase bee-venom products, such as moisturizers, lotions, and lozenges, online or in specialty stores. What problems apitherapy helps and what contraindications this procedure has - this will be discussed in this article. Another study in 100 people with RA showed that combining bee-sting therapy with traditional medications like Methotrexate, Sulfasalazine, and Meloxicam was more effective at reducing pain and joint swelling than treatment with the traditional medication alone (13). Apitherapy uses honey and other products to help treat conditions like arthritis. Renal insufficiency and electrolyte abnormalities such as hyperkalemia may occur secondary to rhabdomyolysis, hemolysis, and acute tubular necrosis. Western medicine has been inconclusive about its benefits, but research is ongoing. Bee venom has been used since ancient times as a healing treatment for various disorders. In susceptible individuals, using topical bee-venom products like serums and moisturizers can also cause adverse reactions, such as itching, hives, and redness (30, 31). With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. We include products we think are useful for our readers. Additionally, it contains phospholipase A2, an enzyme and major allergen that causes inflammation and cell damage. The venom is used in a number of ways and available in many forms. Despite widespread anecdotal reports, there is no scientific consensus as to the safety and effectiveness of bee venom in the management of this disorder.Wesselius 2005, In a study of 26 patients with relapsing-remitting or relapsing secondary progressive MS, bee sting therapy had no effect on disease activity as measured using gadolinium-enhanced magnetic resonance imaging of the brain.Wesselius 2005, Immediate effects after multiple stings include localized pain, swelling, and erythema at individual sting sites. Whether humans began keeping honey bees to harvest honey or to use their stings as a therapeutic tool, we do not know. That said, it’s primarily responsible for the pain associated with bee stings (3). Early systemic symptoms after large-volume envenomation include fatigue, dizziness, nausea, vomiting, and diarrhea. Bee venom has a therapeutic effect in the treatment of acne, atopic dermatitis, alopecia and psoriasis, it also has a great anti-aging potential. After you’ve allowed enough time, you can start to use the cream all over your face. The study was conducted over a 76-week period of immunotherapy with the venom. Bee venom is sometimes used to make medicine. Apitherapy is promoted as alternative medicine for several uses, but its health claims are not supported by scientific evidence. A Norwich, Kansas woman uses a unique treatment for her arthritis; she stings herself with a honey bee, using the venom. Healthline Media does not provide medical advice, diagnosis, or treatment. Other serious adverse effects related to this therapy have also been documented, including hyperventilation, fatigue, appetite loss, extreme pain, increased bleeding risk, and vomiting (29). Apitherapy is an alternative medicine practice that uses bee products — including their venom — to treat and prevent illnesses, pain, and more (6). By reducing inflammation, these compounds are said to promote healing and alleviate pain. Components of Bee Venom. Scientific Name(s): Apis melliferaCommon Name(s): Bee venom, Honeybee venom. This is only a brief summary of general information about this product. The anti-inflammatory effects of bee venom have been shown to especially benefit those with rheumatoid arthritis (RA), a painful inflammatory condition that affects your joints. Meanwhile, bee-venom injections can be administered by healthcare professionals. While you may frequently enjoy honey, you may wonder if honeycomb itself is edible. Bee venom contains at least 18 pharmacologically active components including various Data sources include IBM Watson Micromedex (updated 3 Mar 2021), Cerner Multum™ (updated 1 Mar 2021), ASHP (updated 3 Mar 2021) and others. What’s more, test-tube studies have shown that the venom has powerful antibacterial and anti-inflammatory effects against the acne-causing bacteria Propionibacterium acnes (17, 18). Bee-venom therapy has been used for thousands of years as a natural treatment for a variety of conditions. Based on the available research, it’s safe to say that adverse reactions — ranging from mild to potentially fatal — are common when using bee venom. For example, it’s added to products like extracts, supplements, moisturizers, and serums. The Greeks and Romans used bee products for medicinal purposes as well, where bee venom was used to treat joint pain from arthritis. Bee stings cause human reactions in 2 distinct patterns. Its proponents claim that it offers a wide range of medicinal properties, ranging from reducing inflammation to treating chronic illnesses. Bee Venom is used in pharmaceutical, cosmetic industry, apitherapy. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Our website services, content, and products are for informational purposes only. Dilute bee venom's anti-inflammatory effect (dBVAI) is reversed by intrathecal pretreatment with atropine but not with hexamtehonium, indicating that dBV stimulated an increase in spinal acetylcholine, specifically activating spinal muscarinic receptors. Bee venom and its various usesBee venom and its various usesBee venom and its various usesBee venom and its various usesBee venom and its various uses Contraindications have not been identified. Nonanaphylactic responses to multiple stings often will be apparent within the first several hours; however, severe systemic signs and symptoms have been delayed for up to 24 hours or more.Betten 2006. Will bee venom work? Bee venom, … A single bee sting can produce anaphylaxis in sensitive individuals. Patients allergic to honeybee venom may be particularly sensitive to hymenoptera venoms in general and have been found to be at a higher risk of developing systemic adverse reactions to venom immunotherapy than patients who are sensitive to yellow jacket venom.Muller 1992. Also, honeybee venom has decreased the production of the inflammatory mediator interleukin-1 in rat splenocytes. It may also improve certain medical conditions like rheumatoid arthritis and chronic pain. Stingers should be removed with gentle scraping to prevent further venom injection.Tunget 1993 Mass inoculation of bee venom may induce acute renal failure (ARF), adult respiratory distress syndrome, liver injury, cardiac damage, pancreatitis, skin necrosis, shock hypertension, bleeding, thrombocytopenia, hemolysis, and rhabdomyolysis. Avitoksin itself is actually a kind of substance that can provide a sense of warmth in the blood vessels. More recently, it has been suggested that honeybee venom may alleviate the symptoms and slow the progression of immune-modulated diseases such as arthritis and multiple sclerosis. Bee poisoning refers to a serious bodily reaction to bee venom. Treatment is supportive, with attention to blood pressure, renal function, and maintenance of an open airway. Bee venom is given as a shot for rheumatoid arthritis, nerve pain , multiple sclerosis (MS), reducing the reaction to bee stings in people who are allergic (desensitization) to them (venom immunotherapy), swollen tendons (tendonitis), and muscle conditions such … Although they act as toxins, they have been shown to possess anti-inflammatory and pain-relieving properties. The improvement in EASI scores was also significantly larger than those in the control group at both 2 and 4 weeks (P=0.023 and P=0.022, respectively). Possible side effects, such as an allergic reaction or anaphylactic shock, raise doubts and limit the use of bee venom. The inhibitory effect of bee venom was consistent with that of indomethacin.Park 2004, The Eczema Area and Severity Index (EASI) score was significantly improved in patients with atopic dermatitis who were randomized to receive bee venom emollient in a 4-week, double-blind, controlled trial (n=114). An 8-week study in 120 people with RA found that bee-venom acupuncture, which employed 5–15 bee stings every other day, provided symptom relief effects that were similar to those of traditional RA medications like Methotrexate and Celecoxib (12). Bee sting is probably one of the first natural cures for certain symptoms. In addition to its known regulatory role in bone metabolism, osteopontin has been postulated to be a TH1 cytokine and is involved in TH1-associated immune responses.Konno 2005, Uses for bee venom, although poorly substantiated, include the treatment of diseases of the locomotor systemMund-Hoym 1982 particularly MS. This information should not be used to decide whether or not to take this product. Research has shown that this treatment is safe and effective and can reduce the future risk of serious reactions to bee stings. Honey Bee venom has recently been proven to be safe and maybe therapeutic in a specified dose. Various adverse reactions may occur to bee venom, the severity of which depends on the number of stings sustained. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. The use of propolis and bee venom for curable human disorders was reviewed. The inhibitory actions of bee venom on the generation of inflammation mediators were also effective in synoviocytes from rheumatoid arthritis patients. Regardless of history, monitor any patient with multiple stings. We offer scientifically tested highest quality Georgian Bee Venom Powder. In the same way, venom caused a sharp and immediate decrease in renal blood flow. Transection of the sciatic nerve completely eliminated BVAI on zymosan-induced inflammation, indicating that BVAI is dependent on peripheral nerve integrity and is not a locally mediated anti-inflammatory effect.Kwon 2006. In fact, most available research has been conducted on animals or in test tubes. All currently available evidence supporting this practice is either anecdotal, animal studies, or preliminary evidence, most of which has poor methodology. Additionally, bee-venom therapy can cause serious side effects or even death in highly allergic individuals by causing anaphylaxis, a potentially life-threatening allergic reaction that can make it hard to breathe (28). Evidence from animal studies suggests that bee-venom therapy might help reduce symptoms of autoimmune conditions, such as lupus, encephalomyelitis, and rheumatoid arthritis, by decreasing inflammation and bolstering your immune response (19, 20). It is further suggested that capsaicin-sensitive primary afferents may play differential roles in the development of dynamic and static mechanical allodynia in the bee venom test.Chen 2006, It has been speculated that honeybee venom may prevent the development of or improve the status of patients with rheumatoid arthritis. Cosmetics were applied with or without the intervention (0.06 mg/mL purified bee venom) for 2 weeks.Cao 2015. Loaded with over 250 active substances, bee pollen has gained traction in the health community as a powerful supplement.